Triethylamine → 2-(2-Thienyl)ethyl methanesulphonate

HRID 227377

반응식

HRID 227377 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][OH:8].C(N(CC)CC)C.[CH3:16][S:17](Cl)(=[O:19])=[O:18]>C1COCC1>[CH3:16][S:17]([O:8][CH2:7][CH2:6][C:2]1[S:1][CH:5]=[CH:4][CH:3]=1)(=[O:19])=[O:18]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 794002-Thiopheneethanol

생성물 1

HCID 30477232-(2-Thienyl)ethyl methanesulphonate

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

The 2-(2-thienyl)ethanol (Aldrich, 0.16 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.

출처 및 근거

ORD 기록
ord-89eec4b7916c496884a0a06adf2baf5e
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07560481B2

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