Dichloromethane → 2-(2,3-Dimethylphenyl)propanal

반응식

[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][CH:10]1C[O:11]1.Cl[CH2:14]Cl>>[CH3:1][C:2]1[C:7]([CH3:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9]([CH3:14])[CH:10]=[O:11]

참가 물질

반응물 2

HCID 6344Dichloromethane

HCID 20300557HCID 20300557, 화합물2회

생성물 1

HCID 208317782-(2,3-Dimethylphenyl)propanal수율 100%

실험 절차

2-(2,3-Dimethylphenyl)methyloxirane, compound of formula (XXII), prepared according to example 4 (0.84 g, 5.18 mmol), was dissolved in dry dichloromethane (50 mL) and powdered Cu(BF4)2 hydrate (318 mg) was added at room temperature. After 2 h at room temperature, the mixture was washed with water, dried over Na2SO4 and concentrated under reduced pressure to yield 0.84 g (100%) of the title product.

후처리

washthe mixture was washed with water
dry with materialdried over Na2SO4
concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록: ord-e49b18d0c8b440469b0be54fe9c01420
출처 데이터셋: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09126915B2

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