Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl methanesulfonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Methanesulfonyl chloride | HCID 31297 | — |
| 반응물 | (R)-Solketal | HCID 736056 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl methanesulfonate | HCID 24903512 | — |
반응 단계
The (R)-(−)-2,2-dimethyl-1,3-dioxolane-4-methanol (Aldrich, 0.38 mL, 3.1 mmol), triethylamine (0.85 mL, 6.1 mmol), and methanesulfonyl chloride (0.31 mL, 4.1 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07560481B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-e158575da21c4b91b9a0a6b159c58000 |
| 출처 메모 | uspto-grants-2009_07 |