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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2274681생성일: 2026년 10월 26일

Piperidine → HCID 67075242, 화합물

https://huagongshe.com/reaction/2274681

반응식

참여 물질

역할이름HCID투입량
반응물PiperidineHCID 8082—
반응물(9H-fluoren-9-yl)methyl (S)-3-(4-tert-butoxyphenyl)-1-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-1-oxopropan-2-ylcarbamateHCID 86698526—
생성물HCID 67075242HCID 6707524299.5%

반응 단계

According to the procedure described in the synthesis method of Compound IV-1, (9H-fluoren-9-yl)methyl(S)-3-(4-tert-butoxyphenyl)-1-(((S)-1,1-diethoxypropan-2-yl)(naphthalen-1-ylmethyl)amino)-1-oxopropan-2-ylcarbamate (Compound III-6) (1.34 g, 1.84 mmol) was treated with piperidine and the obtained residue was purified by silica gel column chromatography (eluent: n-hexane:ethyl acetate=9:1, chloroform:methanol=100:0 and 8:2) to obtain the title compound (928 mg, 99%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09126981B2
출처 데이터셋uspto-grants-2015_09
ORD IDord-24bff37de03f4ee5a99fe13074c7e792
출처 메모uspto-grants-2015_09