6-(Trifluoromethyl)indole → 3-iodo-6-(trifluoromethyl)-1H-indole
반응식
F[C:2]1[CH:10]=[C:9]2[C:5]([C:6]([I:20])=[CH:7][N:8]2S(C2C=CC=CC=2)(=O)=O)=[CH:4][CH:3]=1.[F:21][C:22]([F:33])([F:32])C1C=C2C(C=CN2)=CC=1>>[I:20][C:6]1[C:5]2[C:9](=[CH:10][C:2]([C:22]([F:33])([F:32])[F:21])=[CH:3][CH:4]=2)[NH:8][CH:7]=1참가 물질
3
실험 절차
Following the general method as outlined in Intermediate 3, starting from 6-(trifluoromethyl)-1H-indole (0.97 g; 5.24 mmol), 1.60 g (98%) of the title compound was obtained as a red solid, which was used directly without further purification.
출처 및 근거
- ORD 기록
- ord-4f51ff963c2a4360820e13464be79b78
- 출처 데이터셋
- uspto-grants-2015_09
- 특허 번호
- US09126984B2
반응 노트
불러오는 중…