2-Propanone, methylhydrazone → HCID 23635272, 화합물

HRID 2274973

반응식

HRID 2274973 반응식
C(O[CH:4]=[C:5]([C:9](=[O:11])[CH3:10])[C:6](=[O:8])[CH3:7])C.[CH3:12][NH:13][N:14]=[C:15]([CH3:17])[CH3:16]>CCOCC>[CH3:12][N:13]([CH:4]=[C:5]([C:6](=[O:8])[CH3:7])[C:9](=[O:11])[CH3:10])[N:14]=[C:15]([CH3:17])[CH3:16]

참가 물질

4

반응물 2

HCID 798402-Propanone, methylhydrazoneHCID 2404183-(Ethoxymethylene)pentane-2,4-dione

생성물 1

HCID 23635272HCID 23635272, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

반응 조건

온도
0 °C

실험 절차

3-(ethoxymethylene)pentane-2,4-dione (Preparation 2, 8.6 g) was dissolved in Ether (30 mL) and cooled to 0° C. The reaction solution was then slowly treated with 1-methyl-2-(propan-2-ylidene)hydrazine (Preparation 1, 4.8 g) dropwise over 5 minutes, and then warmed and stirred at room temperature overnight. The reaction solution was purified directly by flash column chromatography (Biotage Quad 25; Eluent: 20% EtOH in EtOAc) to afford the title compound as a light red solid. (9.1 g, 84.0%).

후처리

  1. temperaturewarmed
  2. customThe reaction solution was purified directly by flash column chromatography (Biotage Quad 25; Eluent: 20% EtOH in EtOAc)

출처 및 근거

ORD 기록
ord-dd42a8b98f1940ffbbe97bea0aee796b
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09126999B2

연결된 노트

불러오는 중…