2-Methyl-2-(4-vinylphenyl)propanoic acid → 2-(4-Ethylphenyl)-2-methylpropanoic acid
반응식
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]([CH3:14])([CH3:13])[C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1)=[CH2:2]>C(O)C.[C].[Pd]>[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]([CH3:13])([CH3:14])[C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1)[CH3:2]참가 물질
4
실험 절차
2-(4-Vinylphenyl)-2-methylpropanoic acid (58 g) was dissolved in ethanol, and then stirred for 3 hrs under atmospheric hydrogen pressure in the presence of 10% palladium carbon (5.8 g). The catalyst was removed by filtration, and the filtrate was concentrated to obtain a crude product, which was then suspended and washed with hexane to give the title compound (56.5 g, 94.8%).
후처리
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated
- customto obtain a crude product, which
- washwashed with hexane
출처 및 근거
- ORD 기록
- ord-d35939d3b4eb4431b818bd9612521175
- 출처 데이터셋
- uspto-grants-2015_09
- 특허 번호
- US09126931B2
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