2-Tert-butylpropanedioic acid → 4-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester

HRID 2275273노트

반응식

HRID 2275273 반응식
[CH3:1][O:2][C:3]1[N:8]=[C:7]([C:9]([CH3:14])([CH3:13])[C:10]([OH:12])=O)[CH:6]=[CH:5][CH:4]=1.C([CH:19]([C:23]([OH:25])=[O:24])C(O)=O)(C)(C)C>>[C:9]([O:25][C:23](=[O:24])[CH2:19][C:10](=[O:12])[C:9]([C:7]1[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[N:8]=1)([CH3:14])[CH3:13])([CH3:13])([CH3:10])[CH3:7]

참가 물질

3

반응물 2

HCID 2427522-Tert-butylpropanedioic acidHCID 668349942-(6-Methoxypyridin-2-yl)-2-methylpropanoic acid

생성물 1

HCID 668345394-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester

실험 절차

The title compound was synthesized from 2-(6-methoxy-pyridin-2-yl)-2-methyl-propionic acid and mono-tert-butyl malonic acid according to the method used for the synthesis of Compound PR4. The resultant was used for the next step without further purification.

후처리

  1. customused for the synthesis of Compound PR4
  2. customThe resultant was used for the next step without further purification

출처 및 근거

ORD 기록
ord-c8c729664cae41a19f9f987239398a62
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09126931B2

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