Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → 3-Bromo-2-(4-chlorobenzylidene)indan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 2-(p-Chlorobenzylidene)-1-indanone | HCID 367217 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 3-Bromo-2-(4-chlorobenzylidene)indan-1-one | HCID 68748582 | — |
반응 단계
2-(4-chlorobenzylidene)indan-1-one (2.44 g, 9.58 mmol) was dissolved in 35 mL of CCl4. N-bromosuccinimide (1.685 g, 9.58 mmol) and benzoyl peroxide (122 mg, 0.52 mmol) were added in one portion. The solution was then stirred under reflux for one hour and then filtered once cooled to room temperature. The precipitate was separated using flash column chromatography (15:1 Hexanes/EtOAc) provided 14a as white crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09127016B2 |
| 출처 데이터셋 | uspto-grants-2015_09 |
| ORD ID | ord-9f27e8e37682432ba62089a352d77d1e |
| 출처 메모 | uspto-grants-2015_09 |