HCID 57437974, 화합물 → Ethyl 4-amino-5-methylpyridine-3-carboxylate

HRID 227576노트

반응식

HRID 227576 반응식
[N:1]([C:4]1[C:9]([CH3:10])=[CH:8][N:7]=[CH:6][C:5]=1[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[N+]=[N-].[H][H]>C(O)C.[Pd]>[NH2:1][C:4]1[C:9]([CH3:10])=[CH:8][N:7]=[CH:6][C:5]=1[C:11]([O:13][CH2:14][CH3:15])=[O:12]

참가 물질

5

반응물 2

HCID 57437974HCID 57437974, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 46735270Ethyl 4-amino-5-methylpyridine-3-carboxylate수율 98.4%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

0.50 g of material prepared in Step A was dissolved in 15 mL of ethanol. 0.15 g of 10% palladium on carbon was added. The reaction mixture was placed under one atmosphere of hydrogen for 2 hours. The catalyst was removed by filtration. The solvent was removed with a rotary evaporator to afford 0.43 g of the title compound as a white solid.

후처리

  1. customThe catalyst was removed by filtration
  2. customThe solvent was removed with a rotary evaporator

출처 및 근거

ORD 기록
ord-476daa395cd641c88469a6ece3beb246
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07560564B2

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