반응식
FC(F)(F)C(O)=O.[NH2:8][CH2:9][CH:10]([NH:22][C:23](=[O:25])[CH3:24])[C:11]1[C:16]([Cl:17])=[CH:15][C:14]([C:18]([F:21])([F:20])[F:19])=[CH:13][N:12]=1.[F:26][C:27]([F:38])([F:37])[C:28]1[CH:36]=[CH:35][CH:34]=[CH:33][C:29]=1[C:30](O)=[O:31].O.[Cl-].COC1N=C(OC)N=C([N+]2(C)CCOCC2)N=1.C(N(CC)CC)C>C(O)C>[C:23]([NH:22][CH:10]([C:11]1[C:16]([Cl:17])=[CH:15][C:14]([C:18]([F:19])([F:20])[F:21])=[CH:13][N:12]=1)[CH2:9][NH:8][C:30](=[O:31])[C:29]1[CH:33]=[CH:34][CH:35]=[CH:36][C:28]=1[C:27]([F:26])([F:37])[F:38])(=[O:25])[CH3:24]참가 물질
6
반응물 4
생성물 1
시약·촉매·용매 1
실험 절차
108 mg of N-{2-amino-1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}acetamide trifluoroacetate (0.0003 mol), 76 mg of 2-(trifluoromethyl)benzoic acid (0.0003 mol)), 83 mg of 4-(4,6-dimethoxy[1.3.5]triazin-2-yl)-4-methylmorpholinium chloride hydrate (0.0003 mol) and 41 μL of triethylamine (0.0003 mol) are stirred in 3 mL of ethanol at room temperature overnight.
출처 및 근거
- ORD 기록
- ord-289122d3fd244f40bcd2f2a126f0925d
- 출처 데이터셋
- uspto-grants-2009_07
- 특허 번호
- US07560567B2
연결된 노트
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