Trifluoroacetic acid → CC-17369

HRID 2277113노트

반응식

[O:1]=[C:2]1[CH:7]([N:8]2[C:16](=[O:17])[C:15]3[C:10](=[C:11]([OH:26])[CH:12]=[CH:13][C:14]=3[NH:18]C(=O)OC(C)(C)C)[C:9]2=[O:27])[CH2:6][CH2:5][C:4](=[O:28])[NH:3]1.FC(F)(F)C(O)=O>>[NH2:18][C:14]1[CH:13]=[CH:12][C:11]([OH:26])=[C:10]2[C:15]=1[C:16](=[O:17])[N:8]([CH:7]1[CH2:6][CH2:5][C:4](=[O:28])[NH:3][C:2]1=[O:1])[C:9]2=[O:27]

참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 86709850HCID 86709850, 화합물

생성물 1

HCID 86709849CC-17369

실험 절차

deprotecting tert-butyl 2-(2,6-dioxopiperidin-3-yl)-7-hydroxy-1,3-dioxoisoindolin-4-ylcarbamate with trifluoroacetic acid to form 4-amino-2-(2,6-dioxopiperidin-3-yl)-7-hydroxyisoindoline-1,3-dione.

출처 및 근거

ORD 기록: ord-18bd9259e99340c9af02e285f9c67d97
출처 데이터셋: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09133161B2

반응 노트

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