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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2277265생성일: 2026년 10월 26일

(2,2-Difluorocyclopropyl)methanol → N-((2S)-1-((2-(4-((2,2-difluorocyclopropyl)methoxy)-3,5-difluorophenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide

https://huagongshe.com/reaction/2277265

반응식

참여 물질

역할이름HCID투입량
반응물(2,2-Difluorocyclopropyl)methanolHCID 2761401—
반응물N-((2S)-1-((2-(4-(benzyloxy)-3,5-difluorophenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamideHCID 86731341—
생성물N-((2S)-1-((2-(4-((2,2-difluorocyclopropyl)methoxy)-3,5-difluorophenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamideHCID 86731340—

반응 단계

Using N-((2S)-1-((2-(4-(benzyloxy)-3,5-difluorophenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide and (2,2-difluorocyclopropyl)methanol, and in the same manner as in Step A and Step B of Example 4, the title compound was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09133129B2
출처 데이터셋uspto-grants-2015_09
ORD IDord-bce37a9cf9084c6e99d2b6abc3469bd2
출처 메모uspto-grants-2015_09