Bromoacetonitrile → N-((2S)-1-((2-(4-(cyanomethoxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide
반응식
[CH2:1]([O:8][C:9]1[C:14]([F:15])=[CH:13][C:12]([C:16]2[O:17][C:18]3[CH:24]=[C:23]([O:25][CH2:26][C@@H:27]([NH:29][C:30](=[O:32])[CH3:31])[CH3:28])[CH:22]=[CH:21][C:19]=3[N:20]=2)=[CH:11][C:10]=1[F:33])[C:2]1C=CC=CC=1.BrCC#[N:37]>>[C:2]([CH2:1][O:8][C:9]1[C:10]([F:33])=[CH:11][C:12]([C:16]2[O:17][C:18]3[CH:24]=[C:23]([O:25][CH2:26][C@@H:27]([NH:29][C:30](=[O:32])[CH3:31])[CH3:28])[CH:22]=[CH:21][C:19]=3[N:20]=2)=[CH:13][C:14]=1[F:15])#[N:37]참가 물질
3
실험 절차
Using N-((2S)-1-((2-(4-(benzyloxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide and bromoacetonitrile, and in the same manner as in Example 5, the title compound was obtained.
출처 및 근거
- ORD 기록
- ord-b856113cd46046d6a5b04c9768b4b18d
- 출처 데이터셋
- uspto-grants-2015_09
- 특허 번호
- US09133129B2
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