4-tert-Butylphenylboronic acid → 2-[5-(4-tert-butylphenyl)-1-methyl-1H-imidazol-4-yl]pyridine-4-carbonitrile

HRID 2277446노트

반응식

HRID 2277446 반응식
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[C:16]([C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1)([CH3:19])([CH3:18])[CH3:17]>>[C:16]([C:20]1[CH:25]=[CH:24][C:23]([C:2]2[N:6]([CH3:7])[CH:5]=[N:4][C:3]=2[C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)=[CH:22][CH:21]=1)([CH3:19])([CH3:18])[CH3:17]

참가 물질

3

반응물 2

HCID 27343204-tert-Butylphenylboronic acidHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

생성물 1

HCID 904078112-[5-(4-tert-butylphenyl)-1-methyl-1H-imidazol-4-yl]pyridine-4-carbonitrile

실험 절차

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-tert-butylphenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C20H20N4, 317. Found, 317.

출처 및 근거

ORD 기록
ord-8d04eb44a48c4c9b8b7463fa56cc909c
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09133166B2

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