4-(Cyclopropylmethoxy)phenylboronic acid → HCID 90407249, 화합물

반응식

Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[CH:16]1([CH2:19][O:20][C:21]2[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=2)[CH2:18][CH2:17]1>>[CH:16]1([CH2:19][O:20][C:21]2[CH:26]=[CH:25][C:24]([C:2]3[N:6]([CH3:7])[CH:5]=[N:4][C:3]=3[C:8]3[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=3)=[CH:23][CH:22]=2)[CH2:17][CH2:18]1

참가 물질

반응물 2

HCID 41987464-(Cyclopropylmethoxy)phenylboronic acid

HCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

생성물 1

HCID 90407249HCID 90407249, 화합물

실험 절차

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-(cyclopropylmethoxy)phenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C20H18N4O, 331. Found, 331.

출처 및 근거

ORD 기록: ord-85754becdb71491d8b4066ad7d4b08b3
출처 데이터셋: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09133166B2

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