1-Bromo-3-(3-bromopropoxy)propane → 2-[1-(2-methoxyethyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile

HRID 2277478노트

반응식

HRID 2277478 반응식
[NH:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1.BrC[CH2:16][CH2:17][O:18][CH2:19]CCBr>>[CH3:19][O:18][CH2:17][CH2:16][N:1]1[CH:5]=[C:4]([C:6]2[CH:11]=[C:10]([C:12]#[N:13])[CH:9]=[CH:8][N:7]=2)[N:3]=[CH:2]1

참가 물질

3

반응물 2

HCID 112307051-Bromo-3-(3-bromopropoxy)propaneHCID 178510201HCID 178510201, 화합물

생성물 1

HCID 904078292-[1-(2-methoxyethyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile

실험 절차

The title compound was prepared 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and 2-bromo-ethylmethylether according to the procedure for the preparation of Example 35, part A. [M+H] Calc'd for C12H12N4O, 229. Found, 229.

후처리

  1. customfor the preparation of Example 35, part A

출처 및 근거

ORD 기록
ord-c5d178cd2b1f4c9bbf57a3f5696d4795
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09133166B2

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