methyl 2-[1-(triphenylmethyl)-1H-imidazol-4-yl]pyridine-4-carboxylate → methyl 2-(1H-imidazol-4-yl)pyridine-4-carboxylate

HRID 2277485노트

반응식

HRID 2277485 반응식
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[CH:12]=[C:11]([C:13]3[CH:18]=[C:17]([C:19]([O:21][CH3:22])=[O:20])[CH:16]=[CH:15][N:14]=3)[N:10]=[CH:9]2)C=CC=CC=1.N1C=C(C2C=C(C#N)C=CN=2)N=C1>>[NH:8]1[CH:12]=[C:11]([C:13]2[CH:18]=[C:17]([C:19]([O:21][CH3:22])=[O:20])[CH:16]=[CH:15][N:14]=2)[N:10]=[CH:9]1

참가 물질

3

반응물 2

HCID 90407274methyl 2-[1-(triphenylmethyl)-1H-imidazol-4-yl]pyridine-4-carboxylateHCID 178510201HCID 178510201, 화합물

생성물 1

HCID 178498395methyl 2-(1H-imidazol-4-yl)pyridine-4-carboxylate수율 44%

실험 절차

The title compound was prepared in 44% yield (two steps) from methyl 2-[1-(triphenylmethyl)-1H-imidazol-4-yl]pyridine-4-carboxylate according to the procedure for 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile in Example 35. [M+H] Calc'd for C10H9N3O2, 204. Found, 204.

출처 및 근거

ORD 기록
ord-32c50d387c56495f8eb6dc7b7cb881e4
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09133166B2

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