3-Fluoro-4-formylbenzonitrile → HCID 86719432, 화합물
반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH:10]=O)[C:5]#[N:6].[C:12]([CH2:14][C@@H:15]1[N:19]([C:20]2[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=2)[N:18]=[C:17](C2C=CC(C#N)=CC=2)[C@H:16]1C)#[N:13]>>[C:12]([CH2:14][C@@H:15]1[N:19]([C:20]2[CH:21]=[CH:22][C:23]([OH:26])=[CH:24][CH:25]=2)[N:18]=[C:10]([C:9]2[CH:8]=[CH:7][C:4]([C:5]#[N:6])=[CH:3][C:2]=2[F:1])[C@H:16]1[CH3:17])#[N:13]참가 물질
3
실험 절차
4-((4S,5S)-5-(Cyanomethyl)-1-(4-hydroxyphenyl)-4-methyl-4,5-dihydro-1H-pyrazol-3-yl)-3-fluorobenzonitrile was prepared from 3-fluoro-4-formylbenzonitrile following the procedure for the preparation of 4-((4S,5S)-5-(cyanomethyl)-1-(4-hydroxyphenyl)-4-methyl-4,5-dihydro-1H-pyrazol-3-yl)benzonitrile (91G): LC-MS [M+H] 335.
출처 및 근거
- ORD 기록
- ord-eb128a19bc8b4565870259aeca62b508
- 출처 데이터셋
- uspto-grants-2015_09