Acetone Cyanohydrin → 1-Benzyl-5-cyclopropyl-2,2,5-trimethyl-piperazine

HRID 2279190노트

반응식

HRID 2279190 반응식
[CH2:1]([N:8]1[CH2:17][C:16]([CH3:19])([CH3:18])[NH:15][CH2:14][C:9]21[CH2:13]CC[CH2:10]2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:20]1(C(N)(C)CN)C[CH2:21]1.CC(C)(O)C#N>>[CH2:1]([N:8]1[CH2:17][C:16]([CH:18]2[CH2:21][CH2:20]2)([CH3:19])[NH:15][CH2:14][C:9]1([CH3:10])[CH3:13])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 3

HCID 6406Acetone CyanohydrinHCID 435194892-Cyclopropylpropane-1,2-diamineHCID 64842474HCID 64842474, 화합물

생성물 1

HCID 648781021-Benzyl-5-cyclopropyl-2,2,5-trimethyl-piperazine

실험 절차

1-Benzyl-5-cyclopropyl-2,2,5-trimethyl-piperazine was synthesized in analogy to 6-benzyl-8,8-dimethyl-6,9-diaza-spiro[4.5]decane starting from 2-cyclopropyl-propane-1,2-diamine and acetone cyanohydrin.

출처 및 근거

ORD 기록
ord-d57f25a27e784e13971471c0e6711f03
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09133181B2

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