Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Thiophen-2-yl-isoxazole-3-carbaldehyde → {1-[2-(7-Methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-yl}-(5-thiophen-2-yl-isoxazol-3-ylmethyl)-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Thiophen-2-yl-isoxazole-3-carbaldehyde | HCID 2776546 | — |
| 반응물 | 1-[2-(7-Methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-ylamine | HCID 66746530 | — |
| 생성물 | {1-[2-(7-Methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-yl}-(5-thiophen-2-yl-isoxazol-3-ylmethyl)-amine | HCID 46852846 | — |
반응 단계
The title compound is prepared as a yellow oil (57 mg, 52% yield) following Scheme 3 and in analogy to Example 40 using 5-thiophen-2-yl-isoxazole-3-carbaldehyde (43 mg, 0.22 mmol 1.0 eq) and 1-[2-(7-methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-ylamine (70 mg, 0.22 mmol, 1.0 eq) as starting materials.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09133219B2 |
| 출처 데이터셋 | uspto-grants-2015_09 |
| ORD ID | ord-5bc28faa0b824837b39613aa7ed09692 |
| 출처 메모 | uspto-grants-2015_09 |