Thionyl Chloride → HCID 12018889, 화합물

HRID 2280423노트

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HRID 2280423 반응식
[Si:1]([O:8][CH2:9][C:10]1[CH:18]=[CH:17][C:13]([C:14](O)=[O:15])=[CH:12][CH:11]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].S(Cl)([Cl:21])=O>>[Si:1]([O:8][CH2:9][C:10]1[CH:18]=[CH:17][C:13]([C:14]([Cl:21])=[O:15])=[CH:12][CH:11]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 11747545Benzoic acid, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-

생성물 1

HCID 12018889HCID 12018889, 화합물

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온도
80 °C

실험 절차

4-[[t-Butyl(dimethyl)silyl]oxymethyl]benzoic acid (1.44 g) was suspended in thionyl chloride and the mixture was heated to 80° C. for 45 minutes. The resulting solution was concentrated in vacuo. Residual thionyl chloride and HCl were removed by subsequent concentration from toluene (twice). The crude residue was carried on to the next reaction step without purification.

후처리

  1. concentrationThe resulting solution was concentrated in vacuo
  2. customResidual thionyl chloride and HCl were removed by subsequent concentration from toluene (twice)
  3. customThe crude residue was carried on to the next reaction step without purification

출처 및 근거

ORD 기록
ord-61798e268da144de97cf087135e1e13b
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09139532B2

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