Ethyl 2-aminothiazole-4-carboxylate → 2-(3-(4-Fluoro-2-methoxyphenoxy)quinoxaline-2-carboxamido)thiazole-4-carboxylic acid
반응식
[F:1][C:2]1[CH:30]=[CH:29][C:5]([O:6][C:7]2[C:8]([C:17]([NH:19][C:20]3C=C(C=CC=3)C(O)=O)=[O:18])=[N:9][C:10]3[C:15]([N:16]=2)=[CH:14][CH:13]=[CH:12][CH:11]=3)=[C:4]([O:31][CH3:32])[CH:3]=1.FC1C=CC(OC2C(C(O)=O)=NC3C(N=2)=CC=CC=3)=C(OC)C=1.NC1[S:58][CH:59]=[C:60]([C:62]([O:64]CC)=[O:63])[N:61]=1>>[F:1][C:2]1[CH:30]=[CH:29][C:5]([O:6][C:7]2[C:8]([C:17]([NH:19][C:20]3[S:58][CH:59]=[C:60]([C:62]([OH:64])=[O:63])[N:61]=3)=[O:18])=[N:9][C:10]3[C:15]([N:16]=2)=[CH:14][CH:13]=[CH:12][CH:11]=3)=[C:4]([O:31][CH3:32])[CH:3]=1참가 물질
4
반응물 3
생성물 1
실험 절차
2-(3-(4-Fluoro-2-methoxyphenoxy)quinoxaline-2-carboxamido)thiazole-4-carboxylic acid (37) was prepared using a similar experimental procedure as described above for cmpd (36) from 3-(4-fluoro-2-methoxy-phenoxy)quinoxaline-2-carboxylic acid and ethyl 2-aminothiazole-4-carboxylate.