Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetyl chloride → N-cylcohexyl-N-(6,8-dichloro-2-furan-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | Furfural | HCID 7362 | — |
| 반응물 | 3,5-Dichloro-3-pyridylamine | HCID 77886 | — |
| 반응물 | Cyclohexyl isocyanide | HCID 79129 | — |
| 용매 | Perchloric Acid | HCID 24247 | — |
| 생성물 | N-cylcohexyl-N-(6,8-dichloro-2-furan-2-yl-imidazo[1,2-a]pyridin-3-yl)-acetamide | HCID 9886798 | — |
반응 단계
Compound (33) was prepared from 1.0 ml of 2-amino-3,5-dichloropyridine solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of furfural solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%), and reaction with acetyl chloride. Excess acetyl chloride was removed under reduced pressure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849642B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-03d73894ec584ff5a656e71d8024258e |
| 출처 메모 | uspto-grants-2005_02 |