Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-4-methylpyrimidine → cyclohexyl-[7-methyl-2-(1-methyl-1H-pyrrol-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-4-methylpyrimidine | HCID 7939 | — |
| 반응물 | 1-Methyl-1H-pyrrole-2-carbaldehyde | HCID 14504 | — |
| 반응물 | Cyclohexyl isocyanide | HCID 79129 | — |
| 용매 | Perchloric Acid | HCID 24247 | — |
| 생성물 | cyclohexyl-[7-methyl-2-(1-methyl-1H-pyrrol-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-amine | HCID 22591929 | — |
반응 단계
Compound (38) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-4-methylpyrimidine solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of N-methylpyrrole-2-carbaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849642B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-9a13c14e378f4b7cabd9e4ac51904452 |
| 출처 메모 | uspto-grants-2005_02 |