Methyl 6-aminonicotinate → 6-(3-Isopropylureido)nicotinic acid
반응식
[CH:1]([NH:4][C:5](=[O:16])[NH:6][C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][N:15]=1)C(O)=O)([CH3:3])[CH3:2].NC1C=C(C=CN=1)[C:21]([O:23]CC)=[O:22].NC1C=CC(C(OC)=O)=CN=1>>[CH:1]([NH:4][C:5](=[O:16])[NH:6][C:7]1[CH:8]=[CH:9][C:13]([C:21]([OH:23])=[O:22])=[CH:14][N:15]=1)([CH3:2])[CH3:3]참가 물질
4
실험 절차
This compound is prepared analogously to Intermediate Y by replacing ethyl 2-aminoisonicotinate in step 1 with methyl 6-aminonicotinate; [M+H]+ 224.
출처 및 근거
- ORD 기록
- ord-d128626785784b838d72a186ec22b015
- 출처 데이터셋
- uspto-grants-2015_09
- 특허 번호
- US09139586B2
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