HCID 58095033, 화합물 → HCID 58094906, 화합물
반응식
C([N:4]1[CH:8]=[CH:7][N:6]=[C:5]1[C:9]1[S:10][C:11]([Sn](CCCC)(CCCC)CCCC)=[CH:12][C:13]=1[C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:15]=1[Cl:21])C=C.FC(F)(F)S(O[C:41]1[CH:46]=[CH:45][N:44]=[C:43]2[S:47][CH:48]=[CH:49][C:42]=12)(=O)=O>>[Cl:21][C:15]1[CH:16]=[C:17]([Cl:20])[CH:18]=[CH:19][C:14]=1[C:13]1[CH:12]=[C:11]([C:41]2[CH:46]=[CH:45][N:44]=[C:43]3[S:47][CH:48]=[CH:49][C:42]=23)[S:10][C:9]=1[C:5]1[NH:4][CH:8]=[CH:7][N:6]=1참가 물질
3
실험 절차
The title compound was prepared from 1-allyl-2-[3-(2,4-dichlorophenyl)-5-(tributylstannyl)-2-thienyl]-1H-imidazole and thieno[2,3-b]pyridin-4-yl trifluoromethanesulfonate using procedures analogous to those described in Example 8-A, Steps 2 and 3. LC/MS (AA) ES+ 428, 430. 1H NMR (400 MHz, d6 DMSO) δ: 11.97-11.69 (m, 1H), 8.73 (d, J=4.97 Hz, 1H), 8.27 (d, J=5.56 Hz, 1H), 7.88 (s, 1H), 7.77-7.73 (m, 2H), 7.68 (d, J=5.56 Hz, 1H), 7.52-7.43 (m, 2H), 7.22-6.89 (m, 2H).
출처 및 근거
- ORD 기록
- ord-f187f56ffabe4bf6b75d9ea96080b779
- 출처 데이터셋
- uspto-grants-2015_09
- 특허 번호