(E)-2-(3,4-dichlorophenyl)ethenesulfonyl chloride → (E)-4-Cyano-2-(2-(3,4-dichlorophenyl)vinylsulfonamido)benzenesulfonamide

HRID 2283318노트

반응식

HRID 2283318 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([C:8]#[N:9])[CH:5]=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].[Cl:14][C:15]1[CH:16]=[C:17](/[CH:22]=[CH:23]/[S:24](Cl)(=[O:26])=[O:25])[CH:18]=[CH:19][C:20]=1[Cl:21]>>[C:8]([C:6]1[CH:5]=[CH:4][C:3]([S:10]([NH2:13])(=[O:11])=[O:12])=[C:2]([NH:1][S:24](/[CH:23]=[CH:22]/[C:17]2[CH:18]=[CH:19][C:20]([Cl:21])=[C:15]([Cl:14])[CH:16]=2)(=[O:26])=[O:25])[CH:7]=1)#[N:9]

참가 물질

3

반응물 2

HCID 22719686(E)-2-(3,4-dichlorophenyl)ethenesulfonyl chlorideHCID 648978242-Amino-4-cyanobenzenesulfonamide

생성물 1

HCID 57750965(E)-4-Cyano-2-(2-(3,4-dichlorophenyl)vinylsulfonamido)benzenesulfonamide수율 57%

실험 절차

The title compound was synthesized as described for Example 178 in 57% yield, starting from 2-amino-4-cyanobenzenesulfonamide and (E)-2-(3,4-dichlorophenyl)ethenesulfonyl chloride.

출처 및 근거

ORD 기록
ord-24f5f0bef76b4f0ca3ef2ea4c1bdba0d
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09145380B2

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