Methanol → HCID 57750991, 화합물
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][S:10]([NH:13][C:14]2[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][C:15]=2[S:23](=[O:26])(=[O:25])[NH2:24])(=[O:12])=[O:11])=[C:4]([O:27][CH3:28])[CH:3]=1.[CH3:29]O>S(Cl)(Cl)=O>[CH3:29][O:19][C:18](=[O:20])[C:17]1[CH:21]=[CH:22][C:14]([NH:13][S:10]([CH2:9][CH2:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][C:4]=2[O:27][CH3:28])(=[O:12])=[O:11])=[C:15]([S:23](=[O:25])(=[O:26])[NH2:24])[CH:16]=1참가 물질
4
실험 절차
To a solution of 4-[2-(4-chloro-2-methoxy-phenyl)-ethanesulfonylamino]-3-sulfamoyl-benzoic acid (0.18 g, 0.40 mmol) in anhydrous methanol (15 mL), thionyl chloride (1 mL) was added and the mixture was heated at reflux for 18 hours. The volatiles were removed under reduced pressure to give 0.18 g (97% yield) of the title compound.