HCID 22316709, 화합물 → 4-(Methanesulfonyl)-2-methoxyaniline

HRID 2283510노트

반응식

HRID 2283510 반응식
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9]([CH3:12])(=[O:11])=[O:10])[CH:6]=[CH:5][C:4]=1[N+:13]([O-])=O>[Pd].C(O)C>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9]([CH3:12])(=[O:11])=[O:10])[CH:6]=[CH:5][C:4]=1[NH2:13]

참가 물질

4

반응물 1

HCID 22316709HCID 22316709, 화합물

생성물 1

HCID 223167854-(Methanesulfonyl)-2-methoxyaniline수율 98.1%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A suspension of 2-methoxy-4-(methylsulfonyl)-1-nitrobenzene (0.175 g, 0.76 mmol) and palladium on carbon (10 wt %, 0.10 g) in ethanol (10 mL) was stirred under hydrogen at one atmosphere pressure for 18 hours. The reaction was filtered through celite and concentrated to give 2-methoxy-4-(methylsulfonyl)aniline (0.15 g, 92%).

후처리

  1. filtrationThe reaction was filtered through celite and
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-d37c5a4e6ec54e1290828c6f846fdbcb
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09145402B2

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