Ammonium Hydroxide → HCID 66958625, 화합물

반응식

[CH2:1]([N:3]1[C:7]([CH2:8][CH2:9][S:10]([CH3:13])(=[O:12])=[O:11])=[CH:6][C:5]([C:14]([O:16]CC)=O)=[N:4]1)[CH3:2].[OH-].[NH4+:20]>>[CH2:1]([N:3]1[C:7]([CH2:8][CH2:9][S:10]([CH3:13])(=[O:12])=[O:11])=[CH:6][C:5]([C:14]([NH2:20])=[O:16])=[N:4]1)[CH3:2]

참가 물질

반응물 2

HCID 14923Ammonium Hydroxide

HCID 66958712HCID 66958712, 화합물

생성물 1

HCID 66958625HCID 66958625, 화합물

실험 절차

The method described in Part C of Example 10 was used to treat ethyl 1-ethyl-5-(2-methanesulfonylethyl)-1H-pyrazole-3-carboxylate (4.6 g, 17 mmol) with ammonium hydroxide (100 mL). The solid was isolated by filtration and washed with water to provide 3.0 g of 1-ethyl-5-(2-methanesulfonylethyl)-1H-pyrazole-3-carboxamide as a white powder, which was mixed with material from another run.

후처리

customThe solid was isolated by filtration
washwashed with water

출처 및 근거

ORD 기록: ord-cb7a057ef31e46d0a479ae6f38b1ee27
출처 데이터셋: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09145410B2

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