N-cyclopropyl-4-formylbenzamide → 4-(6-((4-Cyanobenzyl)oxy)-1H-benzo[d]imidazol-2-yl)-N-cyclopropylbenzamide
반응식
[C:1]([C:3]1[CH:22]=[CH:21][C:6]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-])=O)=[C:11]([N+:18]([O-])=O)[CH:10]=2)=[CH:5][CH:4]=1)#[N:2].[CH:23]1([NH:26][C:27]([C:29]2[CH:36]=[CH:35][C:32]([CH:33]=O)=[CH:31][CH:30]=2)=[O:28])[CH2:25][CH2:24]1>>[C:1]([C:3]1[CH:22]=[CH:21][C:6]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]3[N:15]=[C:33]([C:32]4[CH:31]=[CH:30][C:29]([C:27]([NH:26][CH:23]5[CH2:25][CH2:24]5)=[O:28])=[CH:36][CH:35]=4)[NH:18][C:11]=3[CH:10]=2)=[CH:5][CH:4]=1)#[N:2]참가 물질
3
실험 절차
Compound 669 was prepared according to the procedure similar to that described in Scheme III from 1-(4-cyanobenzyl)oxy-3,4-dinitrobenzene and 4-(cyclopropylaminocarbonyl)benzaldehyde. [M+H]+ calcd for C25H20N4O2: 409.16; found: 409.04.
출처 및 근거
- ORD 기록
- ord-304c38d36db14f5192cd5319828ac3e1
- 출처 데이터셋
- uspto-grants-2015_09