1-Methyl-1H-indole-5-carboxylic acid → HCID 67688251, 화합물

HRID 2284298

반응식

HRID 2284298 반응식
[C:1]([C:10]1[CH:16]=[CH:15][C:13]([NH2:14])=[CH:12][CH:11]=1)([C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[CH:5][CH:4]=1)=[CH2:2].[CH3:17][N:18]1[C:26]2[C:21](=[CH:22][C:23]([C:27]([OH:29])=O)=[CH:24][CH:25]=2)[CH:20]=[CH:19]1>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([NH:7][C:27]([C:23]2[CH:22]=[C:21]3[C:26](=[CH:25][CH:24]=2)[N:18]([CH3:17])[CH:19]=[CH:20]3)=[O:29])=[CH:8][CH:9]=1)([C:10]1[CH:16]=[CH:15][C:13]([NH:14][C:27]([C:23]2[CH:22]=[C:21]3[C:26](=[CH:25][CH:24]=2)[N:18]([CH3:17])[CH:19]=[CH:20]3)=[O:29])=[CH:12][CH:11]=1)=[CH2:2]

참가 물질

3

반응물 2

HCID 70156011-Methyl-1H-indole-5-carboxylic acidHCID 154713364,4'-(Ethene-1,1-diyl)dianiline

생성물 1

HCID 67688251HCID 67688251, 화합물

실험 절차

Compound 702 was prepared according to the procedure described in Scheme IV from 4,4′-(ethene-1,1-diyl)dianiline and 1-methylindole-5-carboxylic acid. 1H NMR (500 MHz, CDCl3) δ 8.20 (s, 2H), 7.93 (s, 2H), 7.79 (dd, J=1.7, 8.5 Hz, 2H), 7.66 (dd, J=1.7, 6.8 Hz, 4H), 7.42 (d, J=2.3 Hz, 2H), 7.39 (d, J=8.5 Hz, 4H), 7.15 (d, J=2.3 Hz, 2H), 6.61 (d, J=2.9 Hz, 2H), 5.44 (s, 2H), 3.86 (s, 6H).

출처 및 근거

ORD 기록
ord-1e571aa3798947cda293a6bbaabc495a
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09144557B2

연결된 노트

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