2-Aminothiazole → HCID 86674027, 화합물
반응식
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=1)[CH:6]=[CH:5]2.[NH2:20][C:21]1[S:22][CH:23]=[CH:24][N:25]=1.[OH:26][CH:27]1[CH2:32][CH2:31][N:30]([C:33]2[CH:41]=[CH:40][C:36]([C:37](O)=[O:38])=[CH:35][CH:34]=2)[CH2:29][CH2:28]1>>[OH:26][CH:27]1[CH2:28][CH2:29][N:30]([C:33]2[CH:41]=[CH:40][C:36]([C:37]([NH:1][C:2]3[CH:3]=[C:4]4[C:8](=[CH:9][CH:10]=3)[N:7]([C:11]3[CH:19]=[CH:18][C:14]([C:15](=[O:16])[NH:20][C:21]5[S:22][CH:23]=[CH:24][N:25]=5)=[CH:13][CH:12]=3)[CH:6]=[CH:5]4)=[O:38])=[CH:35][CH:34]=2)[CH2:31][CH2:32]1참가 물질
4
실험 절차
Compound 953 was prepared according to the procedure described in Scheme IV from 4-(5-amino-1H-indol-1-yl)benzoic acid, 2-aminothiazole, and 4-(4-hydroxypiperidin-1-yl)benzoic acid. [M+H]+ calcd for C30H27N5O3S: 538.18; found: 539.02.
출처 및 근거
- ORD 기록
- ord-5a1cb1a2b4fc4da5a57c917fec9b30f6
- 출처 데이터셋
- uspto-grants-2015_09