Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isopropylethanediol → 6-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)-2-(2-isopropoxyethoxy)-4-(trifluoromethyl)nicotinonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isopropylethanediol | HCID 7996 | — |
| 반응물 | 2,6-Dichloro-4-(trifluoromethyl)nicotinamide | HCID 2736874 | — |
| 반응물 | 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol | HCID 57968699 | — |
| 생성물 | 6-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)-2-(2-isopropoxyethoxy)-4-(trifluoromethyl)nicotinonitrile | HCID 66726627 | — |
반응 단계
This compound was prepared from 2,6-dichloro-4-(trifluoromethyl)nicotinamide (obtained from Peakdale), 2-isopropoxyethanol, and benzo[c][1,2]oxaborole-1,5(3H)-diol in a similar manner to that of D230. 1H-NMR (400 MHz, DMSO-d6) δ (ppm) 1.72-1.75 (m, 2H), 2.05 (s, 3H), 2.38 (t, J=5.4 Hz, 2H), 4.03 (t, J=5.4 Hz, 2H), 5.03 (s, 2H), 7.13 (d, J=7.8 Hz, 1H), 7.2 (s, 1H), 8.61 (s, 1H), 9.36 (s, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09145429B2 |
| 출처 데이터셋 | uspto-grants-2015_09 |
| ORD ID | ord-0743e16ec2f24e78826963f14a3494a2 |
| 출처 메모 | uspto-grants-2015_09 |