Ethylamine → 2-(Ethylamino)nicotinonitrile
반응식
Cl[C:2]1[N:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH2:10]([NH2:12])[CH3:11]>O>[CH2:10]([NH:12][C:2]1[N:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5])[CH3:11]참가 물질
4
실험 절차
A stirred mixture of 4 g. of 2-chloronicotinonitrile in 200 ml. of a saturated ethanolic ethylamine solution was heated under reflux for 5 hours. The solution was cooled and was diluted with 400 ml. of water. The precipitate of 2-ethylaminonicotinonitrile which formed was collected, air dried and was used directly in the next step without further purification.
후처리
- additionA stirred mixture of 4 g
- temperatureunder reflux for 5 hours
- temperatureThe solution was cooled
- additionwas diluted with 400 ml
출처 및 근거
- ORD 기록
- ord-29844cd14edc4de8bb765a54fa1d30f9
- 출처 데이터셋
- uspto-grants-1982_04
- 특허 번호
- US04324893
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