Acetic Acid → HCID 20542421, 화합물

HRID 2286263노트

반응식

HRID 2286263 반응식
[CH3:1][O:2]/[N:3]=[C:4](/[C:7]1[CH:12]=[N:11][CH:10]=[CH:9][N:8]=1)\[C:5]#[N:6].C(O)(=[O:15])C.OO>O>[CH3:1][O:2]/[N:3]=[C:4](/[C:7]1[CH:12]=[N+:11]([O-:15])[CH:10]=[CH:9][N:8]=1)\[C:5]#[N:6]

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 957691779378-26-0

생성물 1

HCID 20542421HCID 20542421, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
70 °C

실험 절차

A mixture of Z-α-methoxyiminopyrazineacetonitrile (4 g), acetic acid (15 ml) and 30% hydrogen peroxide in water (15 ml) was heated at a temperature of 70° C. over one night. The reaction mixture was concentrated and treated with water and chloroform. The chloroform layer was separated and dried over magnesium sulphate. Evaporation of the solvent and successive crystallization of the residue from alcohol afforded Z-α-methoxyimino-2-pyrazineacetonitrile-4-oxide, m.p. 144°-145° C.

후처리

  1. concentrationThe reaction mixture was concentrated
  2. additiontreated with water and chloroform
  3. customThe chloroform layer was separated
  4. dry with materialdried over magnesium sulphate
  5. customEvaporation of the solvent and successive crystallization of the residue from alcohol

출처 및 근거

ORD 기록
ord-8935e49312484987aa8f2135c8c3ed0f
출처 데이터셋
uspto-grants-1982_04
특허 번호
US04327213

반응 노트

불러오는 중…