Diethyl Ether → HCID 23462418, 화합물

HRID 2286722노트

반응식

HRID 2286722 반응식
[CH3:1][C:2]1[N:3]2[CH:9]=[C:8]([CH2:10]O)[N:7]=[C:4]2[S:5][CH:6]=1.CCOCC.O=S(Cl)[Cl:19]>>[ClH:19].[CH3:1][C:2]1[N:3]2[CH:9]=[C:8]([CH2:10][Cl:19])[N:7]=[C:4]2[S:5][CH:6]=1

참가 물질

4

반응물 3

HCID 3283Diethyl EtherHCID 24386Thionyl ChlorideHCID 13060090HCID 13060090, 화합물

생성물 1

HCID 23462418HCID 23462418, 화합물

실험 절차

10 g of 3-methyl-6-hydroxymethyl-imidazo-(2,1-b)thiazole prepared as described in one of the methods in Example 26, is refluxed for 2 hours in 100 ml of SOCl2. The solution is then cooled, 50 ml of ether are added to yield 11 g of 3-methyl-6-chloromethyl-imidazo-(2,1-b)thiazole hydrochloride; m.p. 280°.

후처리

  1. temperatureThe solution is then cooled

출처 및 근거

ORD 기록
ord-727c2f1682bf41bd8bc140f07adeb124
출처 데이터셋
uspto-grants-1981_05
특허 번호
US04267339

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