Triethylamine → HCID 23462554, 화합물

HRID 2286760노트

반응식

HRID 2286760 반응식
[CH2:1]=[CH:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8].[CH3:10][CH:11]1[C:16](=[O:17])[CH2:15][CH2:14][CH2:13][C:12]1=[O:18].C(N(CC)CC)C>C(OCC)(=O)C>[CH3:10][C:11]1([CH2:1][CH2:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8])[C:16](=[O:17])[CH2:15][CH2:14][CH2:13][C:12]1=[O:18]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 709452-Methyl-1,3-cyclohexanedioneHCID 118047521,7-Octadien-3-one

생성물 1

HCID 23462554HCID 23462554, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

1,7-Octadien-3-one(0.24 g), 2-methyl-1,3-cyclohexanedione(0.5 g) and triethylamine (1 ml) are added to ethyl acetate (10 ml), and the mixture is stirred at room temperature for 24 hours. The triethylamine and acetic acid are evaporated off and the residue is purified by silica gel column chromatography(methylene chloride) to recover 0.39 g of the above-indicated compound. [IR 1700-1730 cm-1, 920 cm-1 ; NMR 1.10 ppm(3H, singlet, --CH3), 4.6-6.0 ppm(3H, multiplet, vinyl)].

후처리

  1. customThe triethylamine and acetic acid are evaporated off
  2. customthe residue is purified by silica gel column chromatography(methylene chloride)
  3. customto recover 0.39 g of the above-indicated compound

출처 및 근거

ORD 기록
ord-4f38ba43deb04cac9a2e07775cec7896
출처 데이터셋
uspto-grants-1981_05
특허 번호
US04267377

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