Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzeneacetonitrile, alpha-hydroxy-3-phenoxy-, (alphaS)- → alpha-Cyano-m-phenoxybenzyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzeneacetonitrile, alpha-hydroxy-3-phenoxy-, (alphaS)- | HCID 93218 | — |
| 반응물 | (3-Fluorophenyl)acetaldehyde | HCID 15811999 | — |
| 반응물 | 4-(3-Fluorophenyl)-2-isopropyl-3-butenoic acid | HCID 53669376 | — |
| 반응물 | Ethyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate | HCID 54533755 | — |
| 반응물 | KOH MeOH Water | HCID 86591755 | — |
| 생성물 | alpha-Cyano-m-phenoxybenzyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate | HCID 53932607 | — |
반응 단계
3-Fluorophenylacetaldehyde is converted into ethyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate using the reaction of Example 9. The ester is hydrolyzed using KOH/MeOH/H2O to 4-(3-fluorophenyl)-2-isopropyl-3-butenoic acid, which is converted to the acid chloride and reacted with α-cyano-m-phenoxybenzyl alcohol to yield α-cyano-m-phenoxybenzyl 4-(3-fluorophenyl)-2-isopropyl-3-butenoate, MS m/e 429 (M+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04267359 |
| 출처 데이터셋 | uspto-grants-1981_05 |
| ORD ID | ord-f7f970fae2fa4bbf93036adf29981be6 |
| 출처 메모 | uspto-grants-1981_05 |