Boron tribromide → 2-(2-Bromoethyl)phenol

HRID 2287476노트

반응식

HRID 2287476 반응식
C[O:2][C:3]1[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=1[CH2:5][CH2:6][Br:7].B(Br)(Br)Br>C(Cl)Cl>[OH:2][C:3]1[CH:11]=[CH:10][CH:9]=[CH:8][C:4]=1[CH2:5][CH2:6][Br:7]

참가 물질

4

반응물 2

HCID 25134Boron tribromideHCID 5781992-Methoxyphenethyl bromide

생성물 1

HCID 139806682-(2-Bromoethyl)phenol

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

To a solution of 2-methoxyphenethyl bromide (1.07 g, 4.98 mmol) in 5 ml of CH2Cl2 was added BBr3 (9.5 ml, 1.0 M in CH2Cl2) at -78° C. and it was allowed to warm to rt over 1.5 h. The reaction mixture was poured into CH2Cl2 and was washed with brine, dried to afford 2-hydroxy phenethyl bromide.

후처리

  1. washwas washed with brine
  2. customdried

출처 및 근거

ORD 기록
ord-e4250c1a9bec4d069c668e183fc2527a
출처 데이터셋
uspto-grants-2000_07
특허 번호
US06083980

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