Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1'-(Diazomethylene)bis(benzene) → (2RS,3SR)-2-diphenylmethoxycarbonyl-5-oxotetrahydrofuran-3-carboxylic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1'-(Diazomethylene)bis(benzene) | HCID 61230 | — |
| 반응물 | Tetrahydro-5-oxofuran-2,3-dicarboxylic acid | HCID 98259 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | (2RS,3SR)-2-diphenylmethoxycarbonyl-5-oxotetrahydrofuran-3-carboxylic Acid | HCID 18705268 | 32% |
반응 단계
262 mg of (2RS,3SR)-5-oxotetrahydrofuran-2,3-dicarboxylic acid in 5 ml of acetone was stirred with 291 mg of diphenyldiazomethane at room temperature for 20 minutes. The reaction solution was evaporated in vacuo to dryness. The residue was purified by silica gel column chromatography [chloroform/methanol=100/1→10/1] to give 163 mg of the title compound as a white powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06083985 |
| 출처 데이터셋 | uspto-grants-2000_07 |
| ORD ID | ord-78f2e9db2e2e4c99a448ea02f49f1e73 |
| 출처 메모 | uspto-grants-2000_07 |