Ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate → 4-(2,2-Dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)-benzoic acid

HRID 2288311

반응식

HRID 2288311 반응식
CC1SC(C2C3C(=CC4C(C=3)=C(C3C=CC(C(O)=O)=CC=3)C=CC=4)C(C)(C)CC=2)=CC=1.[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:48]=[CH:47][C:46]([CH3:49])=[CH:45][CH:44]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([O:60]CC)=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1>>[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:44]=[CH:45][C:46]([CH3:49])=[CH:47][CH:48]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([OH:60])=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1

참가 물질

3

반응물 2

HCID 9933376Ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate2회HCID 186200524-[1 (5-Methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoic acid2회

생성물 1

HCID 98883854-(2,2-Dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)-benzoic acid

실험 절차

By following the procedure employed for the preparation of 4-[1(5-methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoic acid (Compound 4), ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate (Compound 9, 10 mg, 0.02 mmol), was converted into the title compound using LiOH in water (0.2 mL, 0.2 mmol). The title compound was obtained as an off white solid.

출처 및 근거

ORD 기록
ord-669dcb00b939425091e25b9b1e5405a3
출처 데이터셋
uspto-grants-2000_07
특허 번호
US06087505

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