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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2288464생성일: 2026년 10월 26일

Carbonochloridic acid, octyl ester → ethyl 3-[[1-methyl-2-[[N-methyl-4-(N-octoxycarbonylcarbamimidoyl)anilino]methyl]benzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate

https://huagongshe.com/reaction/2288464

반응식

참여 물질

역할이름HCID투입량
반응물Carbonochloridic acid, octyl esterHCID 81956—
반응물1-methyl-2-[N-(4-amidinophenyl)-N-methylaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochlorideHCID 18412298—
생성물ethyl 3-[[1-methyl-2-[[N-methyl-4-(N-octoxycarbonylcarbamimidoyl)anilino]methyl]benzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoateHCID 14040959636%

반응 단계

Prepared analogously to Example 90 from 1-methyl-2-[N-(4-amidinophenyl)-N-methyl-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and n-octyl chloroformate. Yield: 36% of theory, C37H47N7O5 (669.8) ##EQU89##

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06087380
출처 데이터셋uspto-grants-2000_07
ORD IDord-53e206e186d04baa8da8c6c762751ecb
출처 메모uspto-grants-2000_07