Hexane → 6-methoxy-7-methyl-1H-quinolin-4-one
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[CH3:13])[NH:9][CH:8]=[C:7](C(O)=O)[C:6]2=[O:17].CCCCCC>C1(OC2C=CC=CC=2)C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[CH3:13])[NH:9][CH:8]=[CH:7][C:6]2=[O:17]참가 물질
4
실험 절차
6-Methoxy-7-methyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (22 g) was suspended in diphenyl ether (200 ml), and the suspension was heated under reflux overnight. The reaction solution was cooled to room temperature, hexane was then added to the reaction solution, and the precipitated crystal was collected by filtration to give 6-methoxy-7-methyl-1H-quinolin-4-one (16.6 g, yield 93%).
후처리
- temperaturethe suspension was heated
- temperatureunder reflux overnight
- filtrationthe precipitated crystal was collected by filtration
출처 및 근거
- ORD 기록
- ord-4b02311bff3f49bdbaa1d772b7cd53d7
- 출처 데이터셋
- uspto-grants-2009_07
- 특허 번호
- US07560558B2
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