Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 1-(6-chloronaphth-2-ylsulphonyl)piperazine-3-carboxylate → 4-(6-Chloronaphth-2-ylsulphonyl)-2-ethoxycarbonyl-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 1-(6-chloronaphth-2-ylsulphonyl)piperazine-3-carboxylate | HCID 10970999 | — |
| 반응물 | 1-(4-Pyridinyl)-4-piperidinecarbonyl chloride | HCID 11183700 | — |
| 생성물 | 4-(6-Chloronaphth-2-ylsulphonyl)-2-ethoxycarbonyl-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine | HCID 22721818 | 37% |
반응 단계
Using an analogous procedure to that described in Example 1, 1-(4-pyridyl)piperidine-4-carbonyl chloride was reacted with ethyl 1-(6-chloronaphth-2-ylsulphonyl)piperazine-3-carboxylate to give 4-(6-chloronaphth-2-ylsulphonyl)-2-ethoxycarbonyl-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine in 37% yield;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06090813 |
| 출처 데이터셋 | uspto-grants-2000_07 |
| ORD ID | ord-180a490ae52749059a19975b746a860e |
| 출처 메모 | uspto-grants-2000_07 |