Trifluoroacetic acid → HCID 178462039, 화합물

HRID 2289070노트

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HRID 2289070 반응식
[N+:1]([C:4]1[CH:46]=[CH:45][C:7]([CH2:8][O:9][C:10]([N:12]=[C:13]([NH:31][C:32]([O:34][CH2:35][C:36]2[CH:41]=[CH:40][C:39]([N+:42]([O-:44])=[O:43])=[CH:38][CH:37]=2)=[O:33])[NH:14][C@H:15]([CH3:30])[C:16]([NH:18][CH:19]2[CH2:22][N:21](C(OC(C)(C)C)=O)[CH2:20]2)=[O:17])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[F:47][C:48]([F:53])([F:52])[C:49]([OH:51])=[O:50]>ClCCl>[F:47][C:48]([F:53])([F:52])[C:49]([OH:51])=[O:50].[N+:1]([C:4]1[CH:46]=[CH:45][C:7]([CH2:8][O:9][C:10]([N:12]=[C:13]([NH:31][C:32]([O:34][CH2:35][C:36]2[CH:37]=[CH:38][C:39]([N+:42]([O-:44])=[O:43])=[CH:40][CH:41]=2)=[O:33])[NH:14][C@@H:15]([CH3:30])[C:16]([NH:18][CH:19]2[CH2:22][NH:21][CH2:20]2)=[O:17])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 178462040HCID 178462040, 화합물

생성물 1

HCID 178462039HCID 178462039, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a solution of the compound (846 mg), which had been obtained in (1), in anhydrous dichloromethane (10 ml), trifluoroacetic acid (3 ml) was added dropwise under ice cooling. The reaction mixture was then treated in a similar manner to that described in Referential Example 16-(2), whereby the title compound was obtained. The product was provided for use in the subsequent reaction without isolation. Infrared absorption spectrum (Liquid film) νmax cm-1 : 3213, 1758, 1677, 1610, 1600, 1560, 1526.

후처리

  1. additionThe reaction mixture was then treated in a similar manner to that

출처 및 근거

ORD 기록
ord-437a5a27e22f4efbb97f259ff471f619
출처 데이터셋
uspto-grants-2000_07
특허 번호
US06090802

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