4-Nitro-1,3-dihydroisobenzofuran → 4-Amino-1,3-dihydroisobenzofuran

HRID 2290113노트

반응식

HRID 2290113 반응식
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH2:6][O:7][CH2:8]2)([O-])=O.[H][H]>[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH2:6][O:7][CH2:8]2

참가 물질

4

반응물 2

HCID 134722514-Nitro-1,3-dihydroisobenzofuranHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 134722524-Amino-1,3-dihydroisobenzofuran

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

Nitration of the 1,3-dihydro-iso-benzofuran derivatives of Formula 17 provides the 1,3-dihydro-4-nitro-iso-benzofuran compounds of Formula 18. The nitro compounds of Formula 18 are reduced with hydrogen on a suitable catalyst, such as palladium, to give the 1,3-dihydro-4-amino-iso-benzofuran compounds of Formula 19.

출처 및 근거

ORD 기록
ord-7e05cede79f142458dc3fb56cac26c49
출처 데이터셋
uspto-grants-2000_07
특허 번호
US06093838

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