Water → HCID 21279510, 화합물
반응식
[CH3:1][O:2][CH:3]([O:6][CH3:7])[CH2:4]Br.[CH2:8]([S:15][C:16]1[N:20]=[C:19]([SH:21])[NH:18][N:17]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.C[O-].[Na+].O>CN(C)C=O.CCOCC>[CH2:8]([S:15][C:16]1[N:20]=[C:19]([S:21][CH2:4][CH:3]([O:6][CH3:7])[O:2][CH3:1])[NH:18][N:17]=1)[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1참가 물질
7
반응 조건
- 온도
- 110 °C
실험 절차
Bromoacetaldehyde dimethyl acetal (7.8 g) was added portionwise to 3-benzylthio-5-mercapto-1,2,4-triazole (10 g) and sodium methoxide (2.5 g) in dimethylformamide (60 ml) under nitrogen. The mixture was heated at about 110° C. for 5 hours. Addition to water and isolation through ether gave 12.6 g of desired product, mp 73°-76° C.
출처 및 근거
- ORD 기록
- ord-8d28b6102d174d138d3127dc3967212f
- 출처 데이터셋
- uspto-grants-1989_01
- 특허 번호
- US04795483
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