Pyridine → HCID 21279523, 화합물
반응식
[CH2:1]([S:8][C:9]1[N:10]=[C:11]2[S:16][CH2:15][CH:14](O)[N:12]2[N:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N1C=CC=CC=1.S(Cl)(Cl)=O>ClCCl>[CH2:1]([S:8][C:9]1[N:10]=[C:11]2[S:16][CH:15]=[CH:14][N:12]2[N:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
5
실험 절차
The product from stage (b) (7.9 g) was dissolved in dichloromethane (50 ml) and was treated with pyridine (2.7 g), then with thionyl chloride (4.2 g) in dichloromethane (5 ml) dropwise with stirring at 5°-10° C. After 3 hours stirring at room temperature, the solution was washed with water, dilute hydrochloric acid, aqueous sodium bicarbonate solution and water again, dried and run down to give the desired product as a brown oil which was recrystallise from ethanol to give pure product, mp 91°-93° C.
후처리
- washthe solution was washed with water, dilute hydrochloric acid, aqueous sodium bicarbonate solution and water again
- customdried
출처 및 근거
- ORD 기록
- ord-18079cd7768a412ab30425b47240fd48
- 출처 데이터셋
- uspto-grants-1989_01
- 특허 번호
- US04795483
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